Time from infection to disease and infectiousness for Ebola Virus Disease
Citation: Velásquez GE, Aibana O, Ling EJ, Diakite I, Mooring EQ, Murray MB. Time from infection to disease and infectiousness for Ebola virus disease, a systematic review. Clinical Infectious Diseases. 2015 Oct 1;61(7):1135-40.
Summary: This short report summarises a systematic review to find information from which to estimate the incubation and latent periods of Ebola virus disease (EVD). However, there is only limited epidemiological data from discrete 1-day exposures.
Definitions for infectious period (ending upon resolution of wet symptoms or at the time of death), incubation period and latent period are given. Eighteen papers were identified which gave information about single-day exposures, and many of these occurred in healthcare settings. Overall, studies which met their inclusion criteria provided support for a mean incubation period of 6.2 days with a range of 10 to 15 days. The studies reviewed suggest that dry symptoms precede wet ones by 6.1 days.
Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on Ebola but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about Ebola on the basis of this summary alone.
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