Nanoscale materials against coronaviruses in in vitro and animal studies (search done on 4 March 2020)

Added August 27, 2020

Citation: Alizadeh F, Khodavandi A. Systematic Review and Meta-analysis of the Efficacy of Nanoscale Materials against Coronaviruses–Possible Potential Antiviral Agents for SARS-CoV-2. IEEE Transactions on NanoBioscience. 2020 Jul;19(3):485-97.

What is this? Nanoscale materials might be used in the treatment of COVID-19.

In this rapid review, the authors searched for studies on the effects of nanoscale materials against coronaviruses in vitro or in animal models. They restricted their searches to articles published in English and did the search on 4 March 2020. They included 6 in vitro studies, 14 animal model studies and 1 that was both an in vitro and animal model study.

What works: At the time of this review, the included studies showed effectiveness of some nanoscale materials against coronaviruses in in vitro and animal studies.

What doesn’t work: Nothing noted.

What’s uncertain: The relevance of these findings to SARS-CoV-2 is uncertain because of the lack of robust evidence.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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