Longchain polyunsaturated fatty acid supplementation in preterm infants

Added October 10, 2019

Citation: Moon K., Rao S.C., Schulzke S.M., et al. Longchain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database of Systematic Reviews 2016, Issue 12. Art. No.: CD000375.

On pooling of results, no clear long‐term benefits or harms were demonstrated for preterm infants receiving LCPUFA‐supplemented formula. Infants enrolled in the trials were relatively mature and healthy preterm infants. Assessment schedule and methodology, dose and source of supplementation and fatty acid composition of the control formula varied between trials.

There is some controversy over whether long chain polyunsaturated fatty acids (LCPUFA) are essential nutrients for preterm infants as they may not be able to synthesize sufficient amounts of LCPUFA to meet the needs of the developing brain and retina. This review aims to assess whether supplementation of formula milk with LCPUFA is safe and of benefit to preterm infants, with a focus on the effects on visual function, development, and growth of preterm infants.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.

Share