Liver disease and chronic kidney disease patients are at higher risk of severe COVID-19 and death (search done on 14 April 2020)

Added July 25, 2020

Citation: Oyelade T, Alqahtani J, Canciani G. Prognosis of COVID-19 in patients with liver and kidney diseases: an early systematic review and meta-analysis. Tropical Medicine and Infectious Disease. 2020 May 15;5(2):80.

What is this? COVID-19 patients with co-morbidities, such as liver and kidney disease, might be at higher risk of worse outcomes.

In this rapid review, the authors searched for studies reporting clinical characteristics and outcomes of COVID-19 patients with underlying kidney or liver disease. They restricted their searches to studies published in English between 21 November 2019 and 14 April 2020. They included 22 studies (total: 5595 COVID-19 patients), from China (21) and Italy (1), which they assessed to be at a low risk of bias.

What was found: At the time of this review, the included studies found that the prevalence of liver diseases and chronic kidney diseases in patients diagnosed with COVID-19 were 3% and 1%, respectively.

At the time of this review, the included studies found that the proportion of COVID-19 patients who had severe disease was 57% for those with liver disease and 84% for those with chronic kidney disease.

At the time of this review, the included studies found that the mortality rates for COVID-19 patients were 18% for those with liver disease and 53% for those with chronic kidney disease.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

Share