Intermittent iron supplementation for improving nutrition and development in children under 12 years of age

Added November 18, 2013

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There is evidence to suggest that intermittent iron supplementation when compared to placebo or no intervention, is effective in reducing the risk of anaemia in children ≤12 years of age. However, daily supplementation is more effective than intermittent iron supplementation in preventing and controlling anaemia. Intermittent iron supplementation maybe used in settings where daily supplementation cannot be applied.

The use of daily iron supplements in children ≤12 years of age has been associated with several side effects. The use of intermittent supplementation has been proposed as an  effective and safe alternative. The aim of the review was to assess the effects of intermittent supplementation alone or in combination with other vitamins and minerals on nutritional and developmental outcomes in children ≤12 years of age compared with placebo, no intervention or daily intervention.