Nanoscale materials against coronaviruses in in vitro and animal studies (search done on 4 March 2020)
Citation: Alizadeh F, Khodavandi A. Systematic Review and Meta-analysis of the Efficacy of Nanoscale Materials against Coronaviruses–Possible Potential Antiviral Agents for SARS-CoV-2. IEEE Transactions on NanoBioscience. 2020 Jul;19(3):485-97.
What is this? Nanoscale materials might be used in the treatment of COVID-19.
In this rapid review, the authors searched for studies on the effects of nanoscale materials against coronaviruses in vitro or in animal models. They restricted their searches to articles published in English and did the search on 4 March 2020. They included 6 in vitro studies, 14 animal model studies and 1 that was both an in vitro and animal model study.
What works: At the time of this review, the included studies showed effectiveness of some nanoscale materials against coronaviruses in in vitro and animal studies.
What doesn’t work: Nothing noted.
What’s uncertain: The relevance of these findings to SARS-CoV-2 is uncertain because of the lack of robust evidence.