Ventilation techniques and transmission of COVID-19 (search done on 1 May 2020)

Added June 8, 2020

Citation: Schünemann HJ, Khabsa J, Solo K, et al. Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19: A Living Systematic Review of Multiple Streams of Evidence. Annals of Internal Medicine. 2020 May 22.

What is this? Some patients with COVID-19 will become critically ill and need help with their breathing.

In this systematic rapid living review, the authors searched for research relevant to different approaches to oxygenation among patients with coronavirus infections, including COVID-19. They did not restrict their searches by date, type or language of publication and did the most recent search on 1 May 2020. They included 123 studies on ventilation strategies for coronavirus-induced respiratory failure, 12 systematic reviews of randomized trials of non-invasive ventilation in patients with respiratory failure unrelated to coronavirus, 6 studies describing the risk for transmission from aerosol-generating procedures (AGPs), and 15 newly identified systematic reviews updated from a previous review of human studies evaluating the effect of AGPS.

What was found: At the time of this review, the available studies showed that there is indirect and low-certainty evidence that non-invasive ventilation may reduce mortality but may increase risk of transmission of COVID-19 to healthcare workers.

At the time of this review, the available studies showed that the ideal way of providing ventilation to COVID-19 patients was uncertain.


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