Urological conditions and COVID-19 (search done on 8 April 2020)
Citation: Chan VW, Chiu PK, Yee CH, et al. A systematic review on COVID-19: urological manifestations, viral RNA detection and special considerations in urological conditions. World Journal of Urology. 2020 May 27:1-12.
What is this? Some patients with COVID-19 will have existing chronic health problems, such as urological conditions, and information on the manifestations of comorbidities in patients with COVID-19 might provide useful information for patients and those providing their health care.
In this rapid review, the authors searched for studies on the urological clinical manifestations, viral RNA detection and other considerations for COVID-19 patients with urological conditions. They restricted their searches to articles published in English and did the search on 8 April 2020. They included 21 studies (3714 COVID-19 patients) of urinary or gastrointestinal symptoms; 11 studies (195 patients) and 12 studies (325 patients) in which patients had their urine or stools (respectively) tested for SARS-CoV-2 viral RNA; 6 studies reporting a total of 19 cases of COVID-19 in renal transplant recipients and 12 studies (3266 patients) in a meta-analysis of acute kidney injury among COVID-19 patients.
What was found: At the time of this review, the included studies showed that urinary symptoms were unlikely to be a clinical manifestation of COVID-19.
At the time of this review, the included studies showed that viral RNA positivity was detected in both urine and stool samples, suggesting the need for precautions during transurethral or transrectal procedures.
At the time of this review, the included studies suggested that renal transplant patients might have a higher COVID-19 mortality rate than the general population.
At the time of this review, the included studies showed that acute kidney injury leading to mortality was common amongst COVID-19 patients.
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