Systematic review of Zinc fortification trials
Citation: Das J.K., Kumar R., Salam R.A. et al. Systematic review of Zinc fortification trials. Annals of Nutrition and Metabolism. 2013;62(S1):44-56.
Food fortification resulted in significant improvements in plasma zinc concentrations, a functional indicator of zinc status. There were also positive trends for weight gain, as well as serum hemoglobin and copper concentrations.
The World Health Organization estimations state that nearly two billion people may be deficient in in key vitamins and minerals. Infants and pregnant and lactating women may be particularly vulnerable to such deficiencies. This review aimed to assess the efficacy of zinc fortification on several health outcomes including zinc concentrations, linear growth, weight gain and hemoglobin levels in women and children. Eleven studies were included in this review, with data extracted for meta-analysis. The methodological quality of some data was noted to be insufficient to draw certain conclusions. Results showed food fortification with zinc was associated with significant improvements in the plasma zinc concentrations. Significant differences were observed for height velocity although concluding evidence for this result was weak. Estimates for other outcomes, were statistically insignificant, although they showed positive trends.
Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.
If you have found this summary helpful, please consider making a donation. If everyone who looked at our COVID-19 resources gave us just £2 per month, it would fund Evidence Aid’s life-saving work.