Signs and symptoms for diagnosing COVID-19 (search done on 27 April 2020)

Added July 16, 2020

Citation: Struyf T, Deeks JJ, Dinnes J, et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 disease. Cochrane Database of Systematic Reviews. 2020;(7):CD013665.

What is this? When patients with suspected COVID-19 present to primary care or hospital outpatient settings, signs and symptoms might be used to determine if they have the disease.

In this Cochrane Rapid Review, the authors searched for studies that had evaluated the diagnostic accuracy of using signs and symptoms to determine if a person presenting in primary care or to a hospital outpatient setting has COVID‐19. They did not restrict their searches by language of publication and did the search on 27 April 2020. They included 16 studies (total: 7706 participants). A podcast for the review is available here []

What was found: At the time of this review, the included studies showed that the individual signs and symptoms that have been assessed appear to have very poor diagnostic properties. Based on the available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out COVID-19 disease.


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