Pregnancy and coronavirus infection (search done on 13 March 2020)

Added June 10, 2020

Citation: Di Mascio D, Khalil A, Saccone G, et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1-19) during pregnancy: a systematic review and meta-analysis. American journal of obstetrics & gynecology MFM. 2020;2(2):100107.

What is this? Understanding the clinical features of COVID-19 infection during pregnancy will help policy makers involved in clinical practice and service planning.

In this rapid review, the authors searched for articles investigating outcomes related to the mother and baby of coronavirus (CoV) spectrum (SARS, MERS, COVID-19) infections during pregnancy. They restricted their search to articles published in English did the search on 13 March 2020. They included 19 studies (total: 79 pregnancies).

What was found: At the time of this review, the included studies showed that CoV infection during pregnancy is associated with high rates of miscarriage (39.1%), preterm birth (24.3%), preeclampsia (16.2%), cesarean delivery (84%), and perinatal death (11.1%).

At the time of this review, there were no reports of evidence of vertical transmission to newborns.


Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.