Predictors of mortality in hospitalized COVID‐19 patients (search done on 24 April 2020)
Citation: Tian W, Jiang W, Yao J, et al. Predictors of mortality in hospitalized COVID‐19 patients: A systematic review and meta‐analysis. Journal of Medical Virology. 2020 May 22;10.1002/jmv.26050.
What is this? Information on the predictors of mortality for COVID-19 patients might help policy makers and healthcare practitioners.
In this rapid review, the authors searched for studies on predictors of mortality in hospitalized COVID-19 patients. They did not restrict their searches by language and searched for articles published between 1 January 2020 and 24 April 2020. They included 14 studies (total: 4659 patients), which were from China (13 studies, 2025 patients) and the USA (1, 2634).
What was found: At the time of this review, the included studies showed that people with underlying cardiometabolic disease and that present with evidence for acute inflammation and end‐organ damage were at higher risk of mortality due to COVID‐19.
The review also provides an assessment of the evidence from the included studies on other predictors of mortality due to COVID‐19: baseline characteristics (e.g. age, male sex), comorbidities (e.g. hypertension, diabetes, coronary heart disease) and laboratory abnormalities (e.g. cardiac troponin, interleukin‐6, C‐reactive protein, D‐dimer).
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