Predictors of mortality in hospitalized COVID‐19 patients (search done on 24 April 2020)

Added July 25, 2020

Citation: Tian W, Jiang W, Yao J, et al. Predictors of mortality in hospitalized COVID‐19 patients: A systematic review and meta‐analysis. Journal of Medical Virology. 2020 May 22;10.1002/jmv.26050.

What is this? Information on the predictors of mortality for COVID-19 patients might help policy makers and healthcare practitioners.

In this rapid review, the authors searched for studies on predictors of mortality in hospitalized COVID-19 patients. They did not restrict their searches by language and searched for articles published between 1 January 2020 and 24 April 2020. They included 14 studies (total: 4659 patients), which were from China (13 studies, 2025 patients) and the USA (1, 2634).

What was found: At the time of this review, the included studies showed that people with underlying cardiometabolic disease and that present with evidence for acute inflammation and end‐organ damage were at higher risk of mortality due to COVID‐19.

The review also provides an assessment of the evidence from the included studies on other predictors of mortality due to COVID‐19: baseline characteristics (e.g. age, male sex), comorbidities (e.g. hypertension, diabetes, coronary heart disease) and laboratory abnormalities (e.g. cardiac troponin, interleukin‐6, C‐reactive protein, D‐dimer).

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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