Natural product-derived phytochemicals with bioactivity against coronaviruses (search done on 25 March 2020)

Added August 8, 2020

Citation: Mani JS, Johnson JB, Steel JC, et al. Natural product-derived phytochemicals as potential agents against coronaviruses: a review. Virus Research. 2020 Jul 15;284:197989.

What is this? Traditional herbal medicines and purified natural products might be used in the treatment of COVID-19 or provide sources of pharmaceutical drugs.

In this rapid review, the authors searched for studies on extracts and compounds derived from natural products which show potential antiviral bioactivity against coronaviruses. They did not restrict their searches by date of publication the search on 25 March 2020. They included 58 studies.

What was found: At the time of this review, the included studies identified some promising compounds for the inhibition of coronavirus in humans, most of which were polyphenols, contained a substituted fused ring or both.


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