Natural product-derived phytochemicals with bioactivity against coronaviruses (search done on 25 March 2020)

Added August 8, 2020

Citation: Mani JS, Johnson JB, Steel JC, et al. Natural product-derived phytochemicals as potential agents against coronaviruses: a review. Virus Research. 2020 Jul 15;284:197989.

What is this? Traditional herbal medicines and purified natural products might be used in the treatment of COVID-19 or provide sources of pharmaceutical drugs.

In this rapid review, the authors searched for studies on extracts and compounds derived from natural products which show potential antiviral bioactivity against coronaviruses. They did not restrict their searches by date of publication the search on 25 March 2020. They included 58 studies.

What was found: At the time of this review, the included studies identified some promising compounds for the inhibition of coronavirus in humans, most of which were polyphenols, contained a substituted fused ring or both.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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