Middle East respiratory syndrome coronavirus: review of multiple aspects of MERS

Added July 15, 2020

Citation: Dawson P, Malik MR, Parvez F, et al. What have we learned about Middle East respiratory syndrome coronavirus emergence in humans? A systematic literature review. Vector-Borne and Zoonotic Diseases. 2019 Mar 1;19(3):174-92.

What is this? COVID-19 is caused by the respiratory coronavirus, SARS-CoV-2. This is similar to Middle East respiratory syndrome (MERS) and research on MERS-CoV might provide useful information for policy makers responding to the COVID-19 pandemic.

In this systematic review, the authors searched for studies on about MERS-CoV. They restricted their search to articles published in English between 2012 and July 2017 and did the search in 2018. They included 208 studies, covering virology, clinical characteristics, outcomes, therapeutic and preventive options, epidemiology and transmission, animal interface and the search for natural hosts of MERS-CoV.

What was found: At the time of this review, the included studies showed that various potential therapeutics had been identified, but not evaluated in human clinical trials.

At the time of this review, the included studies showed that one potential vaccine for MERS had progressed to phase I trials.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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