Maternal postpartum vitamin A supplementation for the prevention of mortality and morbidity in infancy

Added March 13, 2018

Citation: Gogia S., & Sachdev H.S. Maternal postpartum vitamin A supplementation for the prevention of mortality and morbidity in infancy: a systematic review of randomized controlled trials. International Journal of Epidemiology, 2010;39(5):1217-26

There is no evidence of a mortality or morbidity benefit to the infant following postpartum maternal VAS. Only prevention of infant morbidity or mortality would be sufficient justification for initiating this intervention in public health programs.

Vitamin A deficiency in developing countries may contribute to infant mortality and morbidity. This review aimed to evaluate the effects of postpartum vitamin A supplementation (VAS) on adverse outcomes in infants. Seven randomized or quazi-randomized trials were included for meta-analysis. Results found no evidence of reduced risk of infant mortality. Data for neonatal outcomes was only available from one trial. Two trials showed no evidence of reduced risk of cause-specific mortality with VAS. One trial showed no evidence of a decrease in diarrhea, nor acute respiratory infection. A lack of evidence was identified in this area, suggesting the need for further research in order to draw definitive conclusions on the effects of postpartum VAS.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.

Share