Maternal antenatal multiple micronutrient supplementation for long-term health benefits in children

Added March 13, 2018

Citation: Devakumar D., Fall C.H.D., Sachdev H.S., et al. Maternal antenatal multiple micronutrient supplementation for long-term health benefits in children: a systematic review and meta-analysis. BMC Medicine, (2016). 14, 90. 1-20 http://doi.org/10.1186/s12916-016-0633-3

There is currently no evidence that, compared with iron and folic acid supplementation, routine maternal antenatal multiple micronutrient supplementation (MMN) improves childhood survival, growth, body composition, blood pressure, respiratory or cognitive outcomes.

MMN supplementation has been considered to improve birth outcomes in low- and middle- income countries. This review aimed to assess evidence from long-term follow-up studies of MMN supplementation during pregnancy, in children between ages 0 and 9. Seventeen trials were included for review focusing on the following outcomes; offspring mortality, height, weight and head circumference, anthropometry, body composition, blood pressure, and cognitive and lung function. Trials were assessed for bias using a pre-tested data extraction form. Meta-analysis showed no difference in mortality rates with MMN intervention. Anthropometric studies found no difference at follow-up in weight-for-age z score, height-for-age z score or head circumference. No differences were observed in body composition, blood pressure, or respiratory outcomes, nor cognitive function scores.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.

Share