Immunosuppressed patients are not at higher risk of severe COVID-19 (search done on 31 March 2020)

Added June 23, 2020

Citation: Minotti C, Tirelli F, Barbieri E, et al. How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. Journal of Infection. 2020;81(1):e61-e66.

What is this? Some patients with COVID-19 will become critically ill and there is a need to identify if patients with underlying conditions, such as immunosuppression, are at risk of severe disease.

In this rapid review, the authors searched for research in adults and children with COVID-19 infection and underlying immunosuppression from a variety of causes. They restricted their searches to articles published in English and did their most recent search on 31 March 2020. They included 16 articles (total: 110 immunosuppressed patients), from Asia (13 articles) and Europe (3).

What was found: At the time of this review, the included studies suggest that children and adults who are immunosuppressed are not at higher risk of severe COVID-19 disease.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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