Immunosuppressed patients are not at higher risk of severe COVID-19 (search done on 31 March 2020)

Added June 23, 2020

Citation: Minotti C, Tirelli F, Barbieri E, et al. How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. Journal of Infection. 2020;81(1):e61-e66.

What is this? Some patients with COVID-19 will become critically ill and there is a need to identify if patients with underlying conditions, such as immunosuppression, are at risk of severe disease.

In this rapid review, the authors searched for research in adults and children with COVID-19 infection and underlying immunosuppression from a variety of causes. They restricted their searches to articles published in English and did their most recent search on 31 March 2020. They included 16 articles (total: 110 immunosuppressed patients), from Asia (13 articles) and Europe (3).

What was found: At the time of this review, the included studies suggest that children and adults who are immunosuppressed are not at higher risk of severe COVID-19 disease.


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