Higher versus lower protein intake in formula‐fed low birth weight infants

Added October 8, 2019

Citation: Fenton T.R., Premji S.S., Al‐Wassia H., et al. Higher versus lower protein intake in formula‐fed low birth weight infants. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD003959.

Higher protein intake from formula accelerates weight gain. Limited information is available regarding the impact of higher formula protein intake on long‐term outcomes such as neurodevelopmental abnormalities. Available evidence is not adequate to permit specific recommendations during the initial hospital stay or after discharge.

The ideal quantity of dietary protein for formula‐fed low birth weight infants is still a matter of debate. Protein intake must be sufficient to achieve normal growth without negative effects such as acidosis, uraemia, and elevated levels of circulating amino acids. This review aims to determine mine whether higher versus lower protein intake during the initial hospital stay of formula‐fed preterm infants or low birth weight infants results in improved growth and neurodevelopmental outcomes without evidence of short‐ and long‐term morbidity.


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