Glutamine supplementation to prevent morbidity and mortality in preterm infants

Added October 10, 2019

Citation: Moe‐Byrne T., Brown J.V.E. & McGuire W. Glutamine supplementation to prevent morbidity and mortality in preterm infants. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD001457.

The available trial data do not provide evidence that glutamine supplementation confers important benefits for preterm infants.

Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Glutamine supplementation may improve clinical outcomes in critically ill adults, and it is possible that it may also benefit preterm infants. This review aims to determine the effects of glutamine supplementation on mortality and morbidity in preterm infants.


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