Dilute versus full strength formula in exclusively formula‐fed preterm or low birth weight infants

Added October 8, 2019

Citation: Basuki F., Hadiati D.R., Turner T., et al. Dilute versus full strength formula in exclusively formula‐fed preterm or low birth weight infants. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD007263. DOI: 10.1002/14651858.CD007263.pub2.

There is evidence from three small, old trials at unclear risk of bias that use of dilute formula in preterm or low birth weight formula‐fed infants leads to an important reduction in the time taken for these infants to attain an adequate energy intake. There was no evidence of important differences in feeding intolerance. The impact on serious gastrointestinal problems, including necrotising enterocolitis, was not reported.

Preterm infants have fewer nutrient reserves at birth than full-term infants and often receive artificial formula feeds in the absence of expressed breast milk. The way in which feeds are introduced and advanced in preterm infants varies widely. This review assesses effects of dilute versus full-strength formula on the incidence of necrotising enterocolitis, feeding intolerance, weight gain, length of stay, and time to achieve full calorie intake in exclusively formula‐fed preterm or low birth weight infants.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.

Share