Clinical features of COVID-19 (search done: 10 March 2020)

Added June 2, 2020

Citation: Hu Y, Sun J, Dai Z, et al. Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis. Journal of Clinical Virology. 2020 April 14:104371.

What is this? The COVID-19 pandemic is due to the novel coronavirus, SARS-CoV-2. Understanding this infection better will help policy makers involved in clinical practice and service planning.

In this rapid review, the authors searched for research evaluating the prevalence and severity of the illness for COVID-19 patients. They did not restrict their searches by language of publication and searched for articles published since 1 January 1980 on 10 March 2020. They included 21 clinical studies (total: 47,344 patients), which were from China (20 studies) and Singapore (1).

What was found: At the time of this review, the included studies showed that the most common symptom was fever (86%), followed by cough (66%), fatigue (42%) and shortness of breath (21%).

At the time of this review, the included studies showed that the most prevalent comorbidities were diabetes (45%) and hypertension (42%).

At the time of this review, the included studies showed that most patients with COVID-19 were older adults, with no significant susceptibility difference between males and females.


Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.