Clinical features for diagnosing pneumonia among adults in primary care

Added May 6, 2020

Citation: Htun TP, Sun Y, Chua HL, et al. Clinical features for diagnosis of pneumonia among adults in primary care setting: A systematic and meta-review. Scientific Reports 2019; 9(1): 7600

What is this? Some patients with COVID-19 will develop pneumonia. Existing research may provide information to help diagnose this in adults in primary care.

In this systematic review, the authors searched for studies that assessed clinical predictors of pneumonia in primary care settings. They did not restrict by date of publication and did their final search in March 2018. They included 8 prospective cohort studies, 3 cross-sectional studies, 1 case-control study and 1 retrospective chart review.

What was found: The strongest clinical features of pneumonia are respiratory rate ≥20 per min, temperature ≥38 °C, pulse rate >100 per min and crackles.

The strongest biomarker predictors of pneumonia are procalcitonin (PCT) >0.25 ng/ml and C-reactive protein (CRP) >20 mg/l.

Clinical symptom (cough) and clinical signs (pyrexia, tach- ycardia, tachypnea, and crackles) are limited as a single predictor for diagnosing pneumonia.


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