Cerebrovascular disease leads to more severe COVID-19 disease (research from before 31 March 2020)

Added June 18, 2020

Citation: Aggarwal G, Lippi G, Michael Henry B. Cerebrovascular disease is associated with an increased disease severity in patients with Coronavirus Disease 2019 (COVID-19): A pooled analysis of published literature. International Journal of Stroke. 2020 Jun;15(4):385-9

What is this? Some patients with COVID-19 will become critically ill and it is important to know if patients with underlying conditions, such as cerebrovascular disease, are at increased risk of more severe disease or death.

In this systematic review, the authors searched for studies of COVID-19 patients with cerebrovascular disease. They searched for studies published before 31 March 2020. They included four studies that compared cerebrovascular disease in severe versus non-severe COVID-19 cases (total: 1829 patients) and two studies that compared the rate of cerebrovascular disease in COVID-19 patients who did and did not survive (total: 202 patients).

What was found:  Cerebrovascular disease may increase the risk of patients experiencing severe COVID-19 disease.

The association between cerebrovascular disease and mortality from COVID-19 is uncertain.


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