Antibiotics for treating pneumonia outside hospital

Added March 28, 2020

Citation: Pakhale S, Mulpuru S, Verheij TJM, et al. Antibiotics for community-acquired pneumonia in adult outpatients. Cochrane Database of Systematic Reviews 2014; (10): CD002109

What is this? Some patients with COVID-19 will develop pneumonia, which can become a serious and life-threatening illness. Antibiotics might be used to treat it outside hospital.

In this Cochrane systematic review, the authors searched for randomized trials comparing antibiotic regimens (or antibiotics versus placebo) for patients over 12 years of age with pneumonia, being treated outside hospital. They restricted their search to studies published in peer-reviewed journals but did not restrict by language. They did their searches in March 2014. They included 11 trials (3352 participants) comparing different antibiotics and no studies of antibiotics versus placebo.

What works: Nothing noted.

What doesn’t work: Nothing noted.

What’s uncertain: The included studies do not reveal significant differences in efficacy between various antibiotics when used to treat pneumonia outside hospital, but it is uncertain which regimen is most effective.


Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.