Active case finding in contacts of people with tuberculosis
Citation: Fox G.J., Dobler C.C., Marks G.B. Active case finding in contacts of people with tuberculosis. Cochrane Database of Systematic Reviews 2011, Issue 9. Art. No.: CD008477. DOI: 10.1002/14651858.CD008477.pub2.
There is no evidence to determine if screening direct contacts with people diagnosed with TB increases early detection of TB.
Tuberculosis is a serious infectious disease that affects over nine million people each year. The disease is spread by airborne droplets, which arise in the infected lungs of tuberculosis patients. Despite widespread availability of treatment with effective antibiotic therapies, the disease remains common in many resource limited settings. Authors aimed to determine whether systematic screening all the direct contacts with people with proven TB disease increases the early detection of TB. The review found that there are currently no suitable randomized controlled trials to answer this question. There is insufficient evidence to show whether screening programmes for tuberculosis will improve the rate of diagnosis among contacts of tuberculosis patients or reduce the rate of tuberculosis in the community. Therefore there is a need for further research to determine the benefits of systematic screening of the contacts of tuberculosis patients.
Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the health of refugees and asylum seekers but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the health of refugees and asylum seekers on the basis of this summary alone.
If you have found this summary helpful, please consider making a donation. If everyone who looked at our COVID-19 resources gave us just £2 per month, it would fund Evidence Aid’s life-saving work.