A systematic review of nutritional supplementation in HIV-infected children in resource-limited settings

Added March 21, 2018

Citation: McHenry M.S., Dixit A., Vreeman R.C. A systematic review of nutritional supplementation in HIV-infected children in resource limited settings. Journal of the International Association of Providers of AIDS Care 2015;14(4):313-23

Periodic vitamin A supplementation is associated with reduced mortality. Macronutrient supplementation is linked to improved anthropometrics. More research is needed to determine how nutritional supplementation benefits this particularly vulnerable population.

Malnutrition can be a major cause of death for children. Malnutrition is often treated with nutritional supplementation (NS), however the effects of NS on HIV-infected children are not well known. This review aimed to assess the effects of macro- and micronutrient supplementation on children <18 years old in low- and middle-income countries. Twenty-three studies were included for review, quality was assessed using Effective Public Health Practice Project guidelines. Results showed vitamin A to have a positive effect on mortality rates. Multiple-micronutrient supplementations did not show improvement for measured health outcomes. Ready-to-use foods were associated with improvement in certain anthropometrics.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence the prevention and treatment of malnutrition but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about prevention or treatment of malnutirition on the basis of this summary alone.

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